High Performance Liquid Chromatography
High Performance Liquid Chromatography
The HPLC-A is a High Performance Liquid Chromatography system engineered for detecting diverse organic compounds, unrestricted by analyte boiling points, and widely applied across chemicals, pharmaceuticals, food, nutraceuticals, and cosmetics. It employs a reciprocating dual-plunger parallel pump with alternating pump-head infusion, delivering quiet operation and extended durability. A pressure monitoring function halts the pump automatically when limits are exceeded. The high-pressure pump incorporates a solvent compensation factor for superior infusion accuracy. The UV detector uses direct digital signal output to prevent distortion and interference. Thermal isolation of the deuterium lamp and optics reduces stabilization time. With a flow range of 0.001–9.999 ml/min and 42 MPa maximum pressure, it ensures reliable performance. Power supply is customized to order.
Features:
1. Pump Design and Performance
The system employs a reciprocating double-plunger parallel pump with alternating dual pump heads, delivering low noise levels, extended operational lifespan, and consistent analytical performance.
2. Intelligent Pressure Monitoring and Safety
An integrated process monitoring function continuously tracks system pressure, triggering alarms and automatically halting pump operation when pressure exceeds predefined safety limits.
3. Enhanced Infusion Accuracy
A high-pressure infusion pump incorporating a solvent compensation factor ensures superior infusion precision and accuracy, meeting demanding analytical requirements.
4. UV Detector Signal Integrity
The ultraviolet detector utilizes a direct digital signal output circuit architecture, effectively eliminating signal distortion and external interference for reliable detection results.
5. Full CNC System Operation
A completely computerized numerical control system enables streamlined process operation and accelerated data processing, significantly improving laboratory workflow efficiency.
6. Overall Analytical Capabilities
The instrument delivers stable operation with a well-engineered structure, featuring qualitative repeatability (RSD6 ≤ 0.1%) and quantitative repeatability (RSD6 ≤ 0.3%) for naphthalene/methanol standards.
Technical Data:
| Model | 365HPLC-A |
| High Pressure Constant Flow Pump Technical Performance | |
| Flow Range (ml/min) | 0.001～9.999 |
| Accuracy | ≤±0.3% |
| Stability | RSD≤0.06% |
| Maximum Output Pressure | 42MPa |
| Pressure Pulsation | ＜0.1MPa |
| Power | Custom-made according to the customer’s request |
| UV Detector Technical Performance | |
| Light Source | Deuterium Lamp, guaranteed for 2000 hours.Tungsten Lamp (optional) |
| Wavelength Range | 190～680nm（Deuterium Lamp） / 190～900nm（Deuterium Lamp + Tungsten Lamp） |
| Wavelength Accuracy | ±1nm |
| Spectral Bandwidth | 8nm |
| Flow Cell Volume | 8µL |
| Noise | ±0.25×10-5AU(static) / ±1×10-5AU(Dynamic, Under Specified Conditions) |
| Drift | ±0.4×10-4AU/h(static) / ±2×10-4AU/h (Dynamic, Under Specified Conditions) |
| Minimum Detectable Concentration | 3×10-9g/mL（Naphthalene/Methanol Solution） |
| Power | Custom made according to customer’s request |
| Machine Technical Performance | |
| Qualitative Repeatability | RSD6≤0.1%（Naphthalene/methanol standard） |
| Quantitative Repeatability | RSD6≤0.3%（Naphthalene/methanol standard） |
Applications:
1. Pharmaceutical quality control and drug purity analysis – Detecting active ingredients, impurities, and degradation products to ensure drug safety and regulatory compliance.
2. Food and beverage safety testing – Quantifying additives, preservatives, and contaminants to verify nutritional labels and uphold food safety standards.
3. Cosmetics and personal care ingredient analysis – Identifying and measuring active compounds and potential allergens in formulations to guarantee product efficacy and consumer safety.
4. Biopharmaceutical and biological molecule characterization – Separating and quantifying proteins, antibodies, and other complex biomolecules for purity and potency assessment.
